
Cholesterol After 40
What Your Midlife Body Needs to Know
Cholesterol becomes a bigger deal after 40—and if you’re in the menopause transition, it’s time to get serious about a complete lipid profile. That means not just total cholesterol, but also your LDL, HDL, and triglycerides. These four numbers tell a good part about your heart health, and you can’t afford to ignore them during this stage of your life.
Why This Matters During Menopause
The drop in estrogen doesn’t just affect your mood, sleep, or temperature regulation. It changes the way your body processes fat and cholesterol.
LDL cholesterol (the bad kind) often rises, HDL (the good kind) drops, and triglycerides—the fat stored in your blood—can spike. It’s a perfect storm for heart issues if left unchecked.
A complete lipid profile gives you the clearest view of what’s going on. According to the current CDC at the time of this writing, here’s where your numbers should land:
LDL (bad) cholesterol: less than 100 mg/dL
HDL (good) cholesterol: 50 mg/dL or higher is best
Triglycerides: less than 150 mg/dL
Even a small change—just a 10–15% rise in LDL or triglycerides—can nudge you from healthy into risky territory. And most people won’t feel a thing while it’s happening.
High Cholesterol Could Be You
By the time you reach your mid-40s, the odds of elevated cholesterol jump significantly. More than 77% of adults aged 45–64 going through menopause have high cholesterol—and many have never had a full lipid panel. By age 65, that number is still above 60%. You can’t fix what you don’t measure.
The Long-Term Risk Is Real
High cholesterol and triglycerides are linked to atherosclerosis—plaque buildup in your arteries.
That narrows your blood vessels and increases your risk of heart attack and stroke. The earlier you catch these changes, the better your chance of turning things around.
Even a slightly elevated LDL level during your 40s can increase your risk of heart disease by almost 40% each decade. That’s not just a stat—it’s your future.
Lifestyle Changes to Improve Your Lipid Profile
You can’t control your age or your hormones—but you can take charge of your lifestyle. These three habits make a measurable difference in your cholesterol and triglyceride numbers:
Eat to Support Heart Health
Eat foods rich in soluble fiber like oats, lentils, chia seeds, and apples, and add healthy fats—avocados, olive oil, walnuts, and small fatty fish such as sardines and salmon.
Make Cardio a Daily Habit
You don’t need to train for a marathon. A brisk 30-minute walk, five days a week, can lower LDL, raise HDL, and help keep triglycerides in check.
Limit Sugar and Alcohol
High sugar intake and regular alcohol consumption are two of the fastest ways to raise triglycerides. Hydrate and focus on whole fruit for your sugar fix.
Time to Know Your Numbers
Cholesterol and triglycerides won’t give you warning signs until it’s too late. A full lipid profile is one of the easiest and most important tests, especially during the menopause transition. Ask your provider about testing, track your numbers, and don’t be afraid to make changes. You’ve got one heart. Let’s keep it strong.
If you found something useful here don’t hesitate to click like and don’t forget to subscribe to Fabulous at Forty & Beyond and check out more at INC’s Fabulous at Forty & Beyond – The Menopause Transition pages!
*Health and wellness coaches engage in evidence-based, client-centered processes that facilitate and empower clients to develop and achieve self-determined, health and wellness goals. We do not diagnose, interpret medical data, prescribe or de-prescribe, recommend supplements, provide nutrition consultation or create meal plans, provide exercise prescription or instruction, consult and advise, or provide psychological therapeutic interventions or treatment.